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Mechanism of regulation of stem cell differentiation by matrix stiffness

Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the extracellular matrix is capable of governing stem cell fate determination, but how this biophysical cue is translated into intracellular signaling remains elusive. Here, we eluci...

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Detalles Bibliográficos
Autores principales: Lv, Hongwei, Li, Lisha, Sun, Meiyu, Zhang, Yin, Chen, Li, Rong, Yue, Li, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445995/
https://www.ncbi.nlm.nih.gov/pubmed/26012510
http://dx.doi.org/10.1186/s13287-015-0083-4