Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...

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Detalles Bibliográficos
Autores principales: Coll, Francesc, McNerney, Ruth, Preston, Mark D, Guerra-Assunção, José Afonso, Warry, Andrew, Hill-Cawthorne, Grant, Mallard, Kim, Nair, Mridul, Miranda, Anabela, Alves, Adriana, Perdigão, João, Viveiros, Miguel, Portugal, Isabel, Hasan, Zahra, Hasan, Rumina, Glynn, Judith R, Martin, Nigel, Pain, Arnab, Clark, Taane G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446134/
https://www.ncbi.nlm.nih.gov/pubmed/26019726
http://dx.doi.org/10.1186/s13073-015-0164-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446134/
https://www.ncbi.nlm.nih.gov/pubmed/26019726
http://dx.doi.org/10.1186/s13073-015-0164-0

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