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Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences
Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...
Autores principales: | Coll, Francesc, McNerney, Ruth, Preston, Mark D, Guerra-Assunção, José Afonso, Warry, Andrew, Hill-Cawthorne, Grant, Mallard, Kim, Nair, Mridul, Miranda, Anabela, Alves, Adriana, Perdigão, João, Viveiros, Miguel, Portugal, Isabel, Hasan, Zahra, Hasan, Rumina, Glynn, Judith R, Martin, Nigel, Pain, Arnab, Clark, Taane G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446134/ https://www.ncbi.nlm.nih.gov/pubmed/26019726 http://dx.doi.org/10.1186/s13073-015-0164-0 |
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