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Regulation of axon regeneration by the RNA repair/splicing pathway

Mechanisms governing a neuron’s regenerative ability are important but not well understood. We identified Rtca, RNA 3′-terminal phosphate cyclase, as an inhibitor for axon regeneration. Removal of dRtca cell-autonomously enhanced axon regrowth in the Drosophila central nervous system, whereas its ov...

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Detalles Bibliográficos
Autores principales: Song, Yuanquan, Sretavan, David, Salegio, Ernesto A, Berg, Jim, Huang, Xi, Cheng, Tong, Xiong, Xin, Meltzer, Shan, Han, Chun, Nguyen, Trong-Tuong, Bresnahan, Jacqueline C., Beattie, Michael S., Jan, Lily Yeh, Jan, Yuh Nung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446171/
https://www.ncbi.nlm.nih.gov/pubmed/25961792
http://dx.doi.org/10.1038/nn.4019