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Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease

BACKGROUND AND AIMS: Non-alcoholic steatohepatitis (NASH), the potentially progressive form of nonalcoholic fatty liver disease (NAFLD), is the pandemic liver disease of our time. Although there are several animal models of NASH, consensus regarding the optimal model is lacking. We aimed to compare...

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Detalles Bibliográficos
Autores principales: Machado, Mariana Verdelho, Michelotti, Gregory Alexander, Xie, Guanhua, de Almeida, Thiago Pereira, Boursier, Jerome, Bohnic, Brittany, Guy, Cynthia D., Diehl, Anna Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446215/
https://www.ncbi.nlm.nih.gov/pubmed/26017539
http://dx.doi.org/10.1371/journal.pone.0127991