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Native Contact Density and Nonnative Hydrophobic Effects in the Folding of Bacterial Immunity Proteins
The bacterial colicin-immunity proteins Im7 and Im9 fold by different mechanisms. Experimentally, at pH 7.0 and 10°C, Im7 folds in a three-state manner via an intermediate but Im9 folding is two-state-like. Accordingly, Im7 exhibits a chevron rollover, whereas the chevron arm for Im9 folding is line...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446218/ https://www.ncbi.nlm.nih.gov/pubmed/26016652 http://dx.doi.org/10.1371/journal.pcbi.1004260 |