Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

Contrary to the long-held belief that DNA methylation of terminally differentiated cells is permanent and essentially immutable, post-mitotic neurons exhibit extensive DNA demethylation. The cellular function of active DNA demethylation in neurons, however, remains largely unknown. Tet family protei...

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Detalles Bibliográficos
Autores principales: Yu, Huimei, Su, Yijing, Shin, Jaehoon, Zhong, Chun, Guo, Junjie U., Weng, Yi-Lan, Gao, Fuying, Geschwind, Daniel H., Coppola, Giovanni, Ming, Guo-li, Song, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446239/
https://www.ncbi.nlm.nih.gov/pubmed/25915473
http://dx.doi.org/10.1038/nn.4008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446239/
https://www.ncbi.nlm.nih.gov/pubmed/25915473
http://dx.doi.org/10.1038/nn.4008

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