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SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps

Genome-wide maps of transcription factor (TF) occupancy and regions of open chromatin implicitly contain DNA sequence signals for multiple factors. We present SeqGL, a novel de novo motif discovery algorithm to identify multiple TF sequence signals from ChIP-, DNase-, and ATAC-seq profiles. SeqGL tr...

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Detalles Bibliográficos
Autores principales: Setty, Manu, Leslie, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446265/
https://www.ncbi.nlm.nih.gov/pubmed/26016777
http://dx.doi.org/10.1371/journal.pcbi.1004271