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SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps
Genome-wide maps of transcription factor (TF) occupancy and regions of open chromatin implicitly contain DNA sequence signals for multiple factors. We present SeqGL, a novel de novo motif discovery algorithm to identify multiple TF sequence signals from ChIP-, DNase-, and ATAC-seq profiles. SeqGL tr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446265/ https://www.ncbi.nlm.nih.gov/pubmed/26016777 http://dx.doi.org/10.1371/journal.pcbi.1004271 |