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Cerebral β-Amyloidosis in Mice Investigated by Ultramicroscopy

Alzheimer´s disease (AD) is the most common neurodegenerative disorder. AD neuropathology is characterized by intracellular neurofibrillary tangles and extracellular β-amyloid deposits in the brain. To elucidate the complexity of AD pathogenesis a variety of transgenic mouse models have been generat...

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Detalles Bibliográficos
Autores principales: Jährling, Nina, Becker, Klaus, Wegenast-Braun, Bettina M., Grathwohl, Stefan A., Jucker, Mathias, Dodt, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446269/
https://www.ncbi.nlm.nih.gov/pubmed/26017149
http://dx.doi.org/10.1371/journal.pone.0125418