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Cerebral β-Amyloidosis in Mice Investigated by Ultramicroscopy
Alzheimer´s disease (AD) is the most common neurodegenerative disorder. AD neuropathology is characterized by intracellular neurofibrillary tangles and extracellular β-amyloid deposits in the brain. To elucidate the complexity of AD pathogenesis a variety of transgenic mouse models have been generat...
Autores principales: | Jährling, Nina, Becker, Klaus, Wegenast-Braun, Bettina M., Grathwohl, Stefan A., Jucker, Mathias, Dodt, Hans-Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446269/ https://www.ncbi.nlm.nih.gov/pubmed/26017149 http://dx.doi.org/10.1371/journal.pone.0125418 |
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