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Flexibility Correlation between Active Site Regions Is Conserved across Four AmpC β-Lactamase Enzymes
β-lactamases are bacterial enzymes that confer resistance to β-lactam antibiotics, such as penicillins and cephalosporins. There are four classes of β-lactamase enzymes, each with characteristic sequence and structure properties. Enzymes from class A are the most common and have been well characteri...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446314/ https://www.ncbi.nlm.nih.gov/pubmed/26018804 http://dx.doi.org/10.1371/journal.pone.0125832 |