The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus

Most ligands of epidermal growth factor receptor (EGFR) have the ability to induce EGFR translocation into the nucleus, where EGFR acts as an important transcriptional regulator. Soluble form of heparin-binding EGF-like growth factor (sHB-EGF) is one of the ligands for EGFR in many cell types; howev...

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Detalles Bibliográficos
Autores principales: Korotkevych, Nataliia V., Labyntsev, Andrii Ju., Kolybo, Denis V., Komisarenko, Serhiy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446362/
https://www.ncbi.nlm.nih.gov/pubmed/26016774
http://dx.doi.org/10.1371/journal.pone.0127887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446362/
https://www.ncbi.nlm.nih.gov/pubmed/26016774
http://dx.doi.org/10.1371/journal.pone.0127887

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