Altered LINE-1 Methylation in Mothers of Children with Down Syndrome

Down syndrome (DS, also known as trisomy 21) most often results from chromosomal nondisjunction during oogenesis. Numerous studies sustain a causal link between global DNA hypomethylation and genetic instability. It has been suggested that DNA hypomethylation might affect the structure and dynamics...

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Detalles Bibliográficos
Autores principales: Babić Božović, Ivana, Stanković, Aleksandra, Živković, Maja, Vraneković, Jadranka, Kapović, Miljenko, Brajenović-Milić, Bojana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446367/
https://www.ncbi.nlm.nih.gov/pubmed/26017139
http://dx.doi.org/10.1371/journal.pone.0127423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446367/
https://www.ncbi.nlm.nih.gov/pubmed/26017139
http://dx.doi.org/10.1371/journal.pone.0127423

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