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RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids

Ribosomal ribonucleic acid (RNA), transfer RNA and other biological or synthetic RNA polymers can contain nucleotides that have been modified by the addition of chemical groups. Traditional Sanger sequencing methods cannot establish the chemical nature and sequence of these modified-nucleotide conta...

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Detalles Bibliográficos
Autores principales: Sample, Paul J., Gaston, Kirk W., Alfonzo, Juan D., Limbach, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446411/
https://www.ncbi.nlm.nih.gov/pubmed/25820423
http://dx.doi.org/10.1093/nar/gkv145