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Inosine modifications in human tRNAs are incorporated at the precursor tRNA level

Transfer RNAs (tRNAs) are key adaptor molecules of the genetic code that are heavily modified post-transcriptionally. Inosine at the first residue of the anticodon (position 34; I34) is an essential widespread tRNA modification that has been poorly studied thus far. The modification in eukaryotes re...

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Detalles Bibliográficos
Autores principales: Torres, Adrian Gabriel, Piñeyro, David, Rodríguez-Escribà, Marta, Camacho, Noelia, Reina, Oscar, Saint-Léger, Adélaïde, Filonava, Liudmila, Batlle, Eduard, Ribas de Pouplana, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446420/
https://www.ncbi.nlm.nih.gov/pubmed/25916855
http://dx.doi.org/10.1093/nar/gkv277