Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities

HP0268 is a conserved, uncharacterized protein from Helicobacter pylori. Here, we determined the solution structure of HP0268 using three-dimensional nuclear magnetic resonance (NMR) spectroscopy, revealing that this protein is structurally most similar to a small MutS-related (SMR) domain that exhi...

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Detalles Bibliográficos
Autores principales: Lee, Ki-Young, Lee, Kyu-Yeon, Kim, Ji-Hun, Lee, In-Gyun, Lee, Sung-Hee, Sim, Dae-Won, Won, Hyung-Sik, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446426/
https://www.ncbi.nlm.nih.gov/pubmed/25916841
http://dx.doi.org/10.1093/nar/gkv348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446426/
https://www.ncbi.nlm.nih.gov/pubmed/25916841
http://dx.doi.org/10.1093/nar/gkv348

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