Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation

Hypoxia-inducible factor (HIF)-1α and HIF-2α are the main regulators of cellular responses to hypoxia. Post-translational modifications of HIF-1α and 2α are necessary to modulate their functions. The methylation of non-histone proteins by Set7, an SET domain-containing lysine methyltransferase, is a...

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Detalles Bibliográficos
Autores principales: Liu, Xing, Chen, Zhu, Xu, Chenxi, Leng, Xiaoqian, Cao, Hong, Ouyang, Gang, Xiao, Wuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446437/
https://www.ncbi.nlm.nih.gov/pubmed/25897119
http://dx.doi.org/10.1093/nar/gkv379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446437/
https://www.ncbi.nlm.nih.gov/pubmed/25897119
http://dx.doi.org/10.1093/nar/gkv379

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