Cargando…

Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation

Hypoxia-inducible factor (HIF)-1α and HIF-2α are the main regulators of cellular responses to hypoxia. Post-translational modifications of HIF-1α and 2α are necessary to modulate their functions. The methylation of non-histone proteins by Set7, an SET domain-containing lysine methyltransferase, is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xing, Chen, Zhu, Xu, Chenxi, Leng, Xiaoqian, Cao, Hong, Ouyang, Gang, Xiao, Wuhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446437/ https://www.ncbi.nlm.nih.gov/pubmed/25897119 http://dx.doi.org/10.1093/nar/gkv379

Ejemplares similares

EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation
por: Tang, Jinhua, et al.
Publicado: (2022)

Transcriptional repression of human cad gene by hypoxia inducible factor-1α
por: Chen, Ko-Fan, et al.
Publicado: (2005)

Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6
por: Poornima, Gopalakrishna, et al.
Publicado: (2016)

The DDX6–4E-T interaction mediates translational repression and P-body assembly
por: Kamenska, Anastasiia, et al.
Publicado: (2016)

Probing key DNA contacts in AraR-mediated transcriptional repression of the Bacillus subtilis arabinose regulon
por: Franco, Irina Saraiva, et al.
Publicado: (2007)

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α
por: van Hagen, Martijn, et al.
Publicado: (2010)

eIF4A alleviates the translational repression mediated by classical secondary structures more than by G-quadruplexes
por: Waldron, Joseph A, et al.
Publicado: (2018)

Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia
por: Fu, Zhichao, et al.
Publicado: (2015)

RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs
por: Trotman, Jackson B., et al.
Publicado: (2017)

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

Non-canonical Staphylococcus aureus pathogenicity island repression
por: Miguel-Romero, Laura, et al.
Publicado: (2022)

OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation
por: Liu, Xing, et al.
Publicado: (2022)

Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity
por: Nair, Mahalakshmi, et al.
Publicado: (2007)

Translational repression of thymidylate synthase by targeting its mRNA
por: Garg, Divita, et al.
Publicado: (2013)

RNA-binding protein AUF1 represses Dicer expression
por: Abdelmohsen, Kotb, et al.
Publicado: (2012)

RNA polymerase III transcription is repressed in response to the tumour suppressor ARF
por: Morton, Jennifer P., et al.
Publicado: (2007)

Effects of nucleoid proteins on DNA repression loop formation in Escherichia coli
por: Becker, Nicole A., et al.
Publicado: (2007)

Differential repression of human and mouse TERT genes during cell differentiation
por: Wang, Shuwen, et al.
Publicado: (2009)

A tale of two functions: enzymatic activity and translational repression by carboxyltransferase
por: Meades, Glen, et al.
Publicado: (2010)

Telomere shortening by transgenerational transmission of TNF-α-induced TERRA via ATF7
por: Liu, Binbin, et al.
Publicado: (2019)

Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) Regulates the Expression of B-Cell Lymphoma/Leukemia-2 (Bcl-2) and Promotes the Survival of Mesenchymal Stem Cells (MSCs) via PGC-1α/ERRα Interaction in the Absence of Serum, Hypoxia, and High Glucose Conditions
por: Wang, Min, et al.
Publicado: (2017)

Eukaryotic HMGB proteins as replacements for HU in E. coli repression loop formation
por: Becker, Nicole A., et al.
Publicado: (2008)

Translational repression of mouse mu opioid receptor expression via leaky scanning
por: Song, Kyu Young, et al.
Publicado: (2007)

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2
por: Kim, Hana, et al.
Publicado: (2009)

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
por: Bikard, David, et al.
Publicado: (2013)

Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7
por: Curtis, Helen J., et al.
Publicado: (2017)

Effect of Hypoxia on DDR1 Expression in Pituitary Adenomas
por: Li, Shouchun, et al.
Publicado: (2015)

Hypoxia stabilizes SETDB1 to maintain genome stability
por: Park, Sungryul, et al.
Publicado: (2023)

Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR
por: Samarasinghe, Shivanthi, et al.
Publicado: (2008)

Mlc regulation of Salmonella pathogenicity island I gene expression via hilE repression
por: Lim, Sangyong, et al.
Publicado: (2007)

Different modes and potencies of translational repression by sequence-specific RNA–protein interaction at the 5′-UTR
por: Nie, Minghua, et al.
Publicado: (2006)

PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus
por: Man, Jiang-Hong, et al.
Publicado: (2006)

Delta–Notch—and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
por: Fischer, Andreas, et al.
Publicado: (2007)

Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells
por: Kantidakis, Theodoros, et al.
Publicado: (2010)

Hrp48 and eIF3d contribute to msl-2 mRNA translational repression
por: Szostak, Emilia, et al.
Publicado: (2018)

MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage
por: Paulsen, Teressa, et al.
Publicado: (2021)

MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6
por: Saito, Ken, et al.
Publicado: (2011)

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets
por: Huntzinger, Eric, et al.
Publicado: (2013)

The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter
por: Grocott, Timothy, et al.
Publicado: (2007)

Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 gene
por: Hsu, Ren-Jun, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_c05p5la9kjfbgvet355evbgm92