Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex

The promoter regions of active genes in the eukaryotic genome typically contain nucleosomes post-translationally modified with a trimethyl mark on histone H3 lysine 4 (H3K4), while transcriptional enhancers are marked with monomethylated H3K4. The flavin-dependent monoamine oxidase LSD1 (lysine-spec...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Ah, Chatterjee, Nilanjana, Jennings, Matthew J., Bartholomew, Blaine, Tan, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446439/
https://www.ncbi.nlm.nih.gov/pubmed/25916846
http://dx.doi.org/10.1093/nar/gkv388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446439/
https://www.ncbi.nlm.nih.gov/pubmed/25916846
http://dx.doi.org/10.1093/nar/gkv388

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