New insights into the regulatory mechanisms of ppGpp and DksA on Escherichia coli RNA polymerase–promoter complex

The stringent response modulators, guanosine tetraphosphate (ppGpp) and protein DksA, bind RNA polymerase (RNAP) and regulate gene expression to adapt bacteria to different environmental conditions. Here, we use Atomic Force Microscopy and in vitro transcription assays to study the effects of these...

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Detalles Bibliográficos
Autores principales: Doniselli, Nicola, Rodriguez-Aliaga, Piere, Amidani, Davide, Bardales, Jorge A., Bustamante, Carlos, Guerra, Daniel G., Rivetti, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446441/
https://www.ncbi.nlm.nih.gov/pubmed/25916853
http://dx.doi.org/10.1093/nar/gkv391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446441/
https://www.ncbi.nlm.nih.gov/pubmed/25916853
http://dx.doi.org/10.1093/nar/gkv391

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