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MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer

Mediator of DNA damage checkpoint protein 1 (MDC1) is essential for DNA damage response. However, the role of MDC1 in modulating gene transcription independently of DNA damage and the underlying mechanisms have not been fully defined. Androgen receptor (AR) is the central signaling pathway in prosta...

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Detalles Bibliográficos
Autores principales: Wang, Chunyu, Sun, Hongmiao, Zou, Renlong, Zhou, Tingting, Wang, Shengli, Sun, Shiying, Tong, Changci, Luo, Hao, Li, Yanshu, Li, Zhenhua, Wang, Enhua, Chen, Yuhua, Cao, Liu, Li, Feng, Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446443/
https://www.ncbi.nlm.nih.gov/pubmed/25934801
http://dx.doi.org/10.1093/nar/gkv394