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Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex
SDR5C1 is an amino and fatty acid dehydrogenase/reductase, moonlighting as a component of human mitochondrial RNase P, which is the enzyme removing 5′-extensions of tRNAs, an early and crucial step in tRNA maturation. Moreover, a subcomplex of mitochondrial RNase P catalyzes the N(1)-methylation of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446446/ https://www.ncbi.nlm.nih.gov/pubmed/25925575 http://dx.doi.org/10.1093/nar/gkv408 |