Cargando…

Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex

Mostrar otras versiones (1)

SDR5C1 is an amino and fatty acid dehydrogenase/reductase, moonlighting as a component of human mitochondrial RNase P, which is the enzyme removing 5′-extensions of tRNAs, an early and crucial step in tRNA maturation. Moreover, a subcomplex of mitochondrial RNase P catalyzes the N(1)-methylation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vilardo, Elisa, Rossmanith, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446446/ https://www.ncbi.nlm.nih.gov/pubmed/25925575 http://dx.doi.org/10.1093/nar/gkv408

Ejemplares similares

Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex
por: Vilardo, Elisa, et al.
Publicado: (2015)

A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase—extensive moonlighting in mitochondrial tRNA biogenesis
por: Vilardo, Elisa, et al.
Publicado: (2012)

Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
por: Vilardo, Elisa, et al.
Publicado: (2020)

Substrate recognition and cleavage-site selection by a single-subunit protein-only RNase P
por: Brillante, Nadia, et al.
Publicado: (2016)

Molecular cloning and characterization of the human RNase κ, an ortholog of Cc RNase
por: Economopoulou, Marie-angela I., et al.
Publicado: (2007)

Yeast mitochondrial RNase P, RNase Z and the RNA degradosome are part of a stable supercomplex
por: Daoud, Rachid, et al.
Publicado: (2012)

RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex
por: Krehan, Mario, et al.
Publicado: (2012)

The Amyloid-β-SDR5C1(ABAD) Interaction Does Not Mediate a Specific Inhibition of Mitochondrial RNase P
por: Vilardo, Elisa, et al.
Publicado: (2013)

Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
por: Zhao, Ye, et al.
Publicado: (2015)

Molecular recognition of RhlB and RNase D in the Caulobacter crescentus RNA degradosome
por: Voss, Jarrod E., et al.
Publicado: (2014)

E. coli RNase I exhibits a strong Ca(2+)-dependent inherent double-stranded RNase activity
por: Grünberg, Sebastian, et al.
Publicado: (2021)

Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems
por: Roberts, Gareth A., et al.
Publicado: (2012)

Crystal structure of RNase H3–substrate complex reveals parallel evolution of RNA/DNA hybrid recognition
por: Figiel, Małgorzata, et al.
Publicado: (2014)

RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori
por: Tejada-Arranz, Alejandro, et al.
Publicado: (2021)

Unfolding the HIV-1 reverse transcriptase RNase H domain – how to lose a molecular tug-of-war
por: Zheng, Xunhai, et al.
Publicado: (2016)

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA
por: Vickers, Timothy A., et al.
Publicado: (2015)

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA
por: Hands-Taylor, Katherine L. D., et al.
Publicado: (2010)

Sequence-specific cleavage of dsRNA by Mini-III RNase
por: Głów, Dawid, et al.
Publicado: (2015)

RNase H sequence preferences influence antisense oligonucleotide efficiency
por: Kiełpiński, Łukasz J., et al.
Publicado: (2017)

Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis
por: Fang, Ming, et al.
Publicado: (2009)

RNase L restricts the mobility of engineered retrotransposons in cultured human cells
por: Zhang, Ao, et al.
Publicado: (2014)

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex
por: Chon, Hyongi, et al.
Publicado: (2009)

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase
por: Figiel, Małgorzata, et al.
Publicado: (2017)

Downstream element determines RNase Y cleavage of the saePQRS operon in Staphylococcus aureus
por: Marincola, Gabriella, et al.
Publicado: (2017)

Insights into the molecular determinants involved in cap recognition by the vaccinia virus D10 decapping enzyme
por: Soulière, Marie F., et al.
Publicado: (2010)

Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
por: Srivastav, Rajpal, et al.
Publicado: (2014)

Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli
por: Clarke, Justin E., et al.
Publicado: (2014)

Cross-subunit catalysis and a new phenomenon of recessive resurrection in Escherichia coli RNase E
por: Ali, Nida, et al.
Publicado: (2020)

Identification of RNA helicases with unwinding activity on angiogenin-processed tRNAs
por: Drino, Aleksej, et al.
Publicado: (2023)

Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization
por: Tang, Xiaoli, et al.
Publicado: (2010)

Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry
por: Kime, Louise, et al.
Publicado: (2014)

Distinct and redundant functions of three homologs of RNase III in the cyanobacterium Synechococcus sp. strain PCC 7002
por: Gordon, Gina C, et al.
Publicado: (2018)

Generation of pre-tRNAs from polycistronic operons is the essential function of RNase P in Escherichia coli
por: Mohanty, Bijoy K, et al.
Publicado: (2020)

The putative RNase P motif in the DEAD box helicase Hera is dispensable for efficient interaction with RNA and helicase activity
por: Linden, Martin H., et al.
Publicado: (2008)

RHON1 is a novel ribonucleic acid-binding protein that supports RNase E function in the Arabidopsis chloroplast
por: Stoppel, Rhea, et al.
Publicado: (2012)

Endonucleolytic cleavages by RNase E generate the mature 3′ termini of the three proline tRNAs in Escherichia coli
por: Mohanty, Bijoy K., et al.
Publicado: (2016)

Altered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis
por: Álvarez, Mar, et al.
Publicado: (2013)

RNase AM, a 5′ to 3′ exonuclease, matures the 5′ end of all three ribosomal RNAs in E. coli
por: Jain, Chaitanya
Publicado: (2020)

The recognition of structured elements by a conserved groove distant from domains associated with catalysis is an essential determinant of RNase E
por: Clarke, Justin E, et al.
Publicado: (2023)

Dual expression of CCA-adding enzyme and RNase T in Escherichia coli generates a distinct cca growth phenotype with diverse applications
por: Wellner, Karolin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ub4ipeo2flaqc82r59f8tl6umh