The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks

DNA-end resection, the generation of single-stranded DNA at DNA double strand break (DSB) ends, is critical for controlling the many cellular responses to breaks. Here we show that the conserved DNA damage checkpoint sliding clamp (the 9-1-1 complex) plays two opposing roles coordinating DSB resecti...

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Detalles Bibliográficos
Autores principales: Ngo, Greg H.P., Lydall, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446447/
https://www.ncbi.nlm.nih.gov/pubmed/25925573
http://dx.doi.org/10.1093/nar/gkv409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446447/
https://www.ncbi.nlm.nih.gov/pubmed/25925573
http://dx.doi.org/10.1093/nar/gkv409

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