Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment

The clinical application of doxorubicin (DOX) is compromised by its cardiac toxic effect. Cyclovirobuxine D (CVB-D) is a steroid alkaloid extracted from a traditional Chinese medicine, Buxus microphylla. Our results showed that CVB-D pretreatment markedly attenuated DOX-induced cardiac contractile d...

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Detalles Bibliográficos
Autores principales: Guo, Qian, Guo, Jiabin, Yang, Rong, Peng, Hui, Zhao, Jun, Li, Li, Peng, Shuangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446494/
https://www.ncbi.nlm.nih.gov/pubmed/26075032
http://dx.doi.org/10.1155/2015/151972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446494/
https://www.ncbi.nlm.nih.gov/pubmed/26075032
http://dx.doi.org/10.1155/2015/151972

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