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Single-Round Patterned DNA Library Microarray Aptamer Lead Identification

A method for identifying an aptamer in a single round was developed using custom DNA microarrays containing computationally derived patterned libraries incorporating no information on the sequences of previously reported thrombin binding aptamers. The DNA library was specifically designed to increas...

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Detalles Bibliográficos
Autores principales: Martin, Jennifer A., Mirau, Peter A., Chushak, Yaroslav, Chávez, Jorge L., Naik, Rajesh R., Hagen, Joshua A., Kelley-Loughnane, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446497/
https://www.ncbi.nlm.nih.gov/pubmed/26075138
http://dx.doi.org/10.1155/2015/137489