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Histone H3 mutations—a special role for H3.3 in tumorigenesis?

Brain tumors are the most common solid tumors in children. Pediatric high-grade glioma (HGG) accounts for ∼8–12 % of these brain tumors and is a devastating disease as 70–90 % of patients die within 2 years of diagnosis. The failure to advance therapy for these children over the last 30 years is lar...

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Detalles Bibliográficos
Autores principales: Kallappagoudar, Satish, Yadav, Rajesh K., Lowe, Brandon R., Partridge, Janet F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446520/
https://www.ncbi.nlm.nih.gov/pubmed/25773741
http://dx.doi.org/10.1007/s00412-015-0510-4