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Ethanol contamination of cerebrospinal fluid during standardized sampling and its effect on (1)H-NMR metabolomics

Standardization of body fluid sampling, processing and storage procedures is pivotal to ensure data quality in metabolomics studies. Yet, despite strict adherence to standard sampling guidelines, we detected variable levels of ethanol in the (1)H-NMR spectra of human cerebrospinal fluid (CSF) sample...

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Detalles Bibliográficos
Autores principales: van der Sar, Sonia A., Zielman, Ronald, Terwindt, Gisela M., van den Maagdenberg, Arn M. J. M., Deelder, André M., Mayboroda, Oleg A., Meissner, Axel, Ferrari, Michel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446525/
https://www.ncbi.nlm.nih.gov/pubmed/25935669
http://dx.doi.org/10.1007/s00216-015-8663-9