Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

Lithium is a mood stabilizing agent commonly used for the treatment of bipolar disorder. Here, we investigated the potential neuroprotective effect of lithium against paraquat toxicity and its underlying mechanisms in vitro. SH-SY5Y human neuroblastoma cells were treated with paraquat (PQ) 0.5 mM co...

Descripción completa

Detalles Bibliográficos
Autores principales: Alural, Begum, Ozerdem, Aysegul, Allmer, Jens, Genc, Kursad, Genc, Sermin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446540/
https://www.ncbi.nlm.nih.gov/pubmed/26074776
http://dx.doi.org/10.3389/fncel.2015.00209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446540/
https://www.ncbi.nlm.nih.gov/pubmed/26074776
http://dx.doi.org/10.3389/fncel.2015.00209

Ejemplares similares