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Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

Lithium is a mood stabilizing agent commonly used for the treatment of bipolar disorder. Here, we investigated the potential neuroprotective effect of lithium against paraquat toxicity and its underlying mechanisms in vitro. SH-SY5Y human neuroblastoma cells were treated with paraquat (PQ) 0.5 mM co...

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Detalles Bibliográficos
Autores principales:	Alural, Begum, Ozerdem, Aysegul, Allmer, Jens, Genc, Kursad, Genc, Sermin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446540/ https://www.ncbi.nlm.nih.gov/pubmed/26074776 http://dx.doi.org/10.3389/fncel.2015.00209

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