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Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration

Skeletal muscle satellite cells (SCs) are Pax7(+) myogenic stem cells that reside between the basal lamina and the plasmalemma of the myofiber. In mature muscles, SCs are typically quiescent, but can be activated in response to muscle injury. Depending on the magnitude of tissue trauma, SCs may divi...

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Detalles Bibliográficos
Autores principales: Yablonka-Reuveni, Zipora, Danoviz, Maria E., Phelps, Michael, Stuelsatz, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446549/
https://www.ncbi.nlm.nih.gov/pubmed/26074812
http://dx.doi.org/10.3389/fnagi.2015.00085