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A Novel Simultaneous Determination of Sarpogrelate and its Active Metabolite (M-1) in Human Plasma, Using Liquid Chromatography-Tandem Mass Spectrometry: Clinical Application

BACKGROUND: This study describes a novel analytical method for simultaneously determining sarpogrelate and its metabolite (M-1) in human plasma, using liquid chromatography coupled with tandem mass spectrometry, with electrospray ionization in the positive ion mode. METHODS: Sarpogrelate, M-1, and l...

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Detalles Bibliográficos
Autores principales: Yang, Jeong-Soo, Kim, Jung-Ryul, Cho, EunGi, Huh, Wooseong, Ko, Jae-Wook, Lee, Soo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446576/
https://www.ncbi.nlm.nih.gov/pubmed/26131409
http://dx.doi.org/10.3343/alm.2015.35.4.391