TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP), a mainly Th2 cytokine-mediated disease, often involves mucus secretion. Recent evidence suggests that transmembrane protein 16A (TMEM16A), a calcium-activated Cl(-) channel (CaCC), can regulate mucus secretion from airway epithelium by tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yu, Wang, Xiangdong, Wang, Hong, Jiao, Jian, Li, Ying, Fan, Erzhong, Zhang, Luo, Bachert, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446635/
https://www.ncbi.nlm.nih.gov/pubmed/25749771
http://dx.doi.org/10.4168/aair.2015.7.4.367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446635/
https://www.ncbi.nlm.nih.gov/pubmed/25749771
http://dx.doi.org/10.4168/aair.2015.7.4.367

Ejemplares similares