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TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP), a mainly Th2 cytokine-mediated disease, often involves mucus secretion. Recent evidence suggests that transmembrane protein 16A (TMEM16A), a calcium-activated Cl(-) channel (CaCC), can regulate mucus secretion from airway epithelium by tran...

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Detalles Bibliográficos
Autores principales:	Zhang, Yu, Wang, Xiangdong, Wang, Hong, Jiao, Jian, Li, Ying, Fan, Erzhong, Zhang, Luo, Bachert, Claus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446635/ https://www.ncbi.nlm.nih.gov/pubmed/25749771 http://dx.doi.org/10.4168/aair.2015.7.4.367

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