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Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling

PURPOSE: House-dust-mite (HDM) major allergen Der p2 shares homology and function with Toll-like receptor (TLR) signaling protein myeloid differentiation-2 (MD2) and may lead to airway inflammation. Should Der p2 be internalized by human airway epithelium, it has the theoretical propensity to potent...

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Detalles Bibliográficos
Autores principales: Yin, Sui-Chu, Liao, En-Chih, Chiu, Chih-Liang, Chang, Ching-yun, Tsai, Jaw-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446638/
https://www.ncbi.nlm.nih.gov/pubmed/25749775
http://dx.doi.org/10.4168/aair.2015.7.4.393