Cargando…

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

Lipid droplets (LDs) are intracellular organelles that provide fatty acids (FAs) to cellular processes including synthesis of membranes and production of metabolic energy. While known to move bidirectionally along microtubules (MTs), the role of LD motion and whether it facilitates interaction with...

Descripción completa

Detalles Bibliográficos
Autores principales: Herms, Albert, Bosch, Marta, Reddy, Babu J.N., Schieber, Nicole L., Fajardo, Alba, Rupérez, Celia, Fernández-Vidal, Andrea, Ferguson, Charles, Rentero, Carles, Tebar, Francesc, Enrich, Carlos, Parton, Robert G., Gross, Steven P., Pol, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446796/
https://www.ncbi.nlm.nih.gov/pubmed/26013497
http://dx.doi.org/10.1038/ncomms8176