Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds

BACKGROUND: Retinoic acid receptor-related orphan receptor gamma t (RORγt) is the master regulator of Th17 cell differentiation, which plays a critical role in the pathology of several autoimmune diseases. By directing Th17 cells function, RORγt could be a potential target for drug development for T...

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Detalles Bibliográficos
Autores principales: Ding, Qingfeng, Zhao, Mei, Bai, Chuan, Yu, Bolan, Huang, Zhaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446823/
https://www.ncbi.nlm.nih.gov/pubmed/26021566
http://dx.doi.org/10.1186/s12865-015-0097-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446823/
https://www.ncbi.nlm.nih.gov/pubmed/26021566
http://dx.doi.org/10.1186/s12865-015-0097-9

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