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Quantification of folate metabolism using transient metabolic flux analysis

BACKGROUND: Systematic quantitative methodologies are needed to understand the heterogeneity of cell metabolism across cell types in normal physiology, disease, and treatment. Metabolic flux analysis (MFA) can be used to infer steady state fluxes, but it does not apply for transient dynamics. Kineti...

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Detalles Bibliográficos
Autores principales: Tedeschi, Philip M, Johnson-Farley, Nadine, Lin, Hongxia, Shelton, Laura M, Ooga, Takushi, Mackay, Gillian, Van Den Broek, Niels, Bertino, Joseph R, Vazquez, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446824/
https://www.ncbi.nlm.nih.gov/pubmed/26023330
http://dx.doi.org/10.1186/s40170-015-0132-6