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Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells

BACKGROUND: Mechanical ventilation plays a central role in the injury of premature lungs. However, the mechanisms by which mechanical signals trigger an inflammatory cascade to promote lung injury are not well-characterized. Transient receptor potential vanilloid 4 (TRPV4), a calcium-permeable mecha...

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Detalles Bibliográficos
Autores principales: Nayak, Pritha S., Wang, Yulian, Najrana, Tanbir, Priolo, Lauren M., Rios, Mayra, Shaw, Sunil K., Sanchez-Esteban, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446903/
https://www.ncbi.nlm.nih.gov/pubmed/26006045
http://dx.doi.org/10.1186/s12931-015-0224-4