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Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells
BACKGROUND: Mechanical ventilation plays a central role in the injury of premature lungs. However, the mechanisms by which mechanical signals trigger an inflammatory cascade to promote lung injury are not well-characterized. Transient receptor potential vanilloid 4 (TRPV4), a calcium-permeable mecha...
Autores principales: | Nayak, Pritha S., Wang, Yulian, Najrana, Tanbir, Priolo, Lauren M., Rios, Mayra, Shaw, Sunil K., Sanchez-Esteban, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446903/ https://www.ncbi.nlm.nih.gov/pubmed/26006045 http://dx.doi.org/10.1186/s12931-015-0224-4 |
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