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17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells

BACKGROUND: To sustain cell growth, cancer cells exhibit an altered metabolism characterized by increased lipogenesis. Stearoyl-CoA desaturase-1 (SCD-1) catalyzes the production of monounsaturated fatty acids that are essential for membrane biogenesis, and is required for cell proliferation in many...

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Detalles Bibliográficos
Autores principales: Belkaid, Anissa, Duguay, Sabrina R., Ouellette, Rodney J., Surette, Marc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446951/
https://www.ncbi.nlm.nih.gov/pubmed/26022099
http://dx.doi.org/10.1186/s12885-015-1452-1