Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood

BACKGROUND: As one of the genetic mechanisms for adaptive immunity, V(D)J recombination generates an enormous repertoire of T-cell receptors (TCRs). With the development of high-throughput sequencing techniques, systematic exploration of V(D)J recombination becomes possible. Multiplex PCR has been p...

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Detalles Bibliográficos
Autores principales: Gao, Fan, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446965/
https://www.ncbi.nlm.nih.gov/pubmed/26018870
http://dx.doi.org/10.1186/s12896-015-0153-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446965/
https://www.ncbi.nlm.nih.gov/pubmed/26018870
http://dx.doi.org/10.1186/s12896-015-0153-9

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