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The Maze of APP Processing in Alzheimer’s Disease: Where Did We Go Wrong in Reasoning?
Why has Alzheimer’s disease (AD) remained a conundrum today? The main reason is the stagnation in understanding the origins of plaques and tangles. While they are widely thought to be the products of the “aberrant” pathways, we believe that plaques and tangles result from natural aging. From this ne...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447002/ https://www.ncbi.nlm.nih.gov/pubmed/26052267 http://dx.doi.org/10.3389/fncel.2015.00186 |