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The Maze of APP Processing in Alzheimer’s Disease: Where Did We Go Wrong in Reasoning?

Why has Alzheimer’s disease (AD) remained a conundrum today? The main reason is the stagnation in understanding the origins of plaques and tangles. While they are widely thought to be the products of the “aberrant” pathways, we believe that plaques and tangles result from natural aging. From this ne...

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Detalles Bibliográficos
Autor principal: Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447002/
https://www.ncbi.nlm.nih.gov/pubmed/26052267
http://dx.doi.org/10.3389/fncel.2015.00186