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Immunoreactivity of the fully humanized therapeutic antibody PankoMab-GEX™ is an independent prognostic marker for breast cancer patients

BACKGROUND: Mucin-1 (MUC1, CD227), more widely known as CA15-3, is an abundantly expressed epithelial cell surface antigen and has evolved to be the most predictive serum tumour marker in breast cancer. PankoMab-GEX™, which is currently being evaluated for its therapeutic efficacy in a phase IIb cli...

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Detalles Bibliográficos
Autores principales: Heublein, Sabine, Mayr, Doris, Egger, Markus, Karsten, Uwe, Goletz, Steffen, Angele, Martin, Gallwas, Julia, Jeschke, Udo, Ditsch, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447018/
https://www.ncbi.nlm.nih.gov/pubmed/25986064
http://dx.doi.org/10.1186/s13046-015-0152-7