Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage

Arginine methylation is a post-translational modification required for the maintenance of genomic integrity. Cells deficient in protein arginine methyltransferase 1 (PRMT1) have DNA damage signaling defects, defective checkpoint activation and extensive genomic instability. Herein we identify the DN...

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Detalles Bibliográficos
Autores principales: Gurunathan, Gayathri, Yu, Zhenbao, Coulombe, Yan, Masson, Jean-Yves, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447065/
https://www.ncbi.nlm.nih.gov/pubmed/26020839
http://dx.doi.org/10.1038/srep10475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447065/
https://www.ncbi.nlm.nih.gov/pubmed/26020839
http://dx.doi.org/10.1038/srep10475

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