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Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage
Arginine methylation is a post-translational modification required for the maintenance of genomic integrity. Cells deficient in protein arginine methyltransferase 1 (PRMT1) have DNA damage signaling defects, defective checkpoint activation and extensive genomic instability. Herein we identify the DN...
Autores principales: | Gurunathan, Gayathri, Yu, Zhenbao, Coulombe, Yan, Masson, Jean-Yves, Richard, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447065/ https://www.ncbi.nlm.nih.gov/pubmed/26020839 http://dx.doi.org/10.1038/srep10475 |
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