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Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

Toll-like receptors (TLRs) are sensors that recognize molecular patterns from viruses, bacteria, and fungi to initiate innate immune responses to invading pathogens. The emergence of highly pathogenic coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory...

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Detalles Bibliográficos
Autores principales: Totura, Allison L., Whitmore, Alan, Agnihothram, Sudhakar, Schäfer, Alexandra, Katze, Michael G., Heise, Mark T., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447251/
https://www.ncbi.nlm.nih.gov/pubmed/26015500
http://dx.doi.org/10.1128/mBio.00638-15