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Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection
Toll-like receptors (TLRs) are sensors that recognize molecular patterns from viruses, bacteria, and fungi to initiate innate immune responses to invading pathogens. The emergence of highly pathogenic coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory...
Autores principales: | Totura, Allison L., Whitmore, Alan, Agnihothram, Sudhakar, Schäfer, Alexandra, Katze, Michael G., Heise, Mark T., Baric, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447251/ https://www.ncbi.nlm.nih.gov/pubmed/26015500 http://dx.doi.org/10.1128/mBio.00638-15 |
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